Quantitative analysis of fetal DNA in maternal plasma

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WU Jing()
HUANG Yan-yi()
CHEN Xiao-man()
Journal Title:
Volume 9, Issue 05, 2006
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  • [1]李智,夏铁安.孕妇外周血中胎儿有核红细胞分离与检测.中华医学遗传学杂志,1998,15:111-114.
  • [2]Cha D,Hogan B,Bohmer RM,et al.A simple and sensitive erythroblast scoring system to identify fetal cells in maternal blood.Prenat Diagn,2003,23:68-73.
  • [3]Lo YM,Corbetta N,Chamberlain PE,et al.Presence of fetal DNA in maternal plasma and serum.Lancet,1997,350:485-487.
  • [4]Choe J,Hwang D,Kim KC,et al.Fetal gender determination and Bcl I polymorphism using nucleated erythrocytes in maternal blood.J Histochem Cytochem,2005,53:323-327.
  • [5]Zolotukhina TV,Shilova NV,Voskoboeva EY.Analysis of cell-free fetal DNA in plasma and serum of pregnant women.J Histochem Cytochem,2005,53:297-299.
  • [6]Lo YM,Tein MS,Lau TK,et al.Quantitative analysis of fetal DNA in maternal plasma and serum:implications for noninvasive prenatal diagnosis.Am J Hum Genet,1998,62:768-775.
  • [7]Bischoff FZ,Lewis DE,Simpson JL.Cell-free fetal DNA in maternal blood:kinetics,source and structure.Hum Reprod Update,2005,11:59-67.
  • [8]Zhong XY,Holzgreve W,Hahn S.Detection of fetal Rhesus D and sex using fetal DNA from maternal plasma by mutiplex polymerase chain reaction.BJOG,2000,107:766-769.
  • [9]Orzinska A,Guz K,Brojer E,et al.Examination of the RHD gene by non-invasive method in plasma of alloimmunized mother allowed to abandon invasive procedures and to deliver a healthy child.Ginekol Pol,2004,75:963-965.
  • [10]Wilson RD.Genetics Committee of the SOGC.Cell-free fetal DNA in the maternal circulation and its future uses in obstetrics.J Obstet Gynaecol Can,2005,27:54-62.
  • [11]Cotter AM,Martin CM,O'Leary J J,et al.Increased fetal RhD gene in the maternal circulation in early pregnancy is associated with an increased risk of pre-eclampsia.BJOG,2005,112:584-587.
  • [12]Leung TN,Zhang J,Lau TK,et al.Maternal plasma fetal DNA as a marker for preeterm labour(Letter).Lancet,1998,352:1904-1905.
  • [13]Lo YM,Leung TN,Tein MS,et al.Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia.Clin Chem,1999,45:184-188.
  • [14]Galbiati S,Smid M,Gambini D,et al.Fetal DNA detection in maternal plasma throughout gestation.Hum Genet,2005,117:243-248.
  • [15]周荣家,程汉华,余其兴,等.SRY基因与性别决定.中华医学遗传学杂志,1995,10:287-288.
  • [16]Sinclair AH,Berta P,Palmer MS,et al.A gene from the human sex-determining region encodes a protein with a homology to a conserved DNA binding motif.Nature,1990,346:240.
  • [17]Birch L,English CA,O'Donoghue K,et al.Accurate and robust quantification of circulating fetal and total DNA in maternal plasma from 5 to 41 weeks of gestation.Clin Chem,2005,51:312-320.
  • [18]Hamada H,Arinami T,Kubo T,et al.Fetal nucleated cells in maternal peripheral blood:frequency and relationship to gestational age.Hum Genet,1993,91:427-432.
  • [19]Lo YM,Zhang J,Leung TN,et al.Rapid clearance of fetal DNA from maternal plasma.Am J Hum Genet,1999,64:218-224.
  • [20]Kolialexi A,Tsangaris GT,Antsaklis A,et al.Rapid clearance of fetal cells from maternal circulation after delivery.Ann N Y Acad Sci,2004,1022:113-118.
  • [21]Lo YM,Lau TK,Zhang J,et al.Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21.Clin Chem,1999,45:1747-1751.
  • [22]Spencer K,de Kok JB,Swinkels DW.Increased total cell-free DNA in the serum of pregnant women carrying a fetus affected by trisomy 21.Prenat Diagn,2003,23:580-583.
  • [23]Ho SS,Damayanti Z,Chua WY,et al.Non-invasive prenatal diagnosis of fetal gender using real-time polymerase chain reaction amplification of SRY in maternal plasma.Ann Acad Med Singapore,2004,33(5Suppl):S61-S62.
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