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Evaluation of the Levels of Cytokines (Interleukin-1β, Interleukin-6, Tumor Necrosis Factor-α) in Preterm Labor with Intraamniotic Infection
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PERINATAL MEDICINE
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1007-9408.1998.03.001
- Key Word:
- 分娩,早产;感染;白细胞介素1;白细胞介素6;肿瘤坏死因子
Abstract： 目的 探讨与感染有关的细胞因子(interleukin-1β,IL-1β)、(interleukin-6,IL-6)、(tumor necrosis factor-a,TNF-α)在早产中的应用.方法 取30例早产孕妇和31例足月临产孕妇,46例足月未临产孕妇的血和羊水标本,分别行血IL-6、羊水中IL-1β、IL-6及TNF-α和胎盘行病理检查.结果 (1)早产组的羊水中IL-1β、IL-6、TNF-α及血浆中IL-6水平显著高于妊娠足月组(包括临产组和未临产组).早产组中有宫内感染孕妇的细胞因子水平显著高于无宫内感染者.(2)羊水和血浆中IL-6水平有明显的相关性.结论 早产有宫内感染者血浆及羊水中细胞因子水平高于无宫内感染者,血浆IL-6水平与羊水IL-6水平密切相关.
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