Objective To summarize the effectiveness of improved surgical techniques of corpus callosotomy in patients with refractory epilepsy. Methods A retrospective analysis was performed on the clinical data of 36 patients with refractory epilepsy, admitted to our hospital from July 2003 to July 2010; the incision via improved small bone window was summarized on skin incision,bone flap design, surgical advantages and disadvantages, and intraoperative precautions. Results A S-shaped or an approximately U-shaped incision was made in the right frontal scalp.The craniotomy was performed with a small trapezoid bone window (the topline,the baseline and the height:2,4 and 2.5 cm,respectively). With the help of microscope,the extent of sectioning consisted of the anterior 2/3 of the total length of the corpus callosum.Post-surgical outcome was assessed according to Engel's scale scores for 9 to 12 months of follow-up:6 patients were in grade Ⅰ,14 in grade Ⅱ,12 in grade Ⅲ and 4 in grade Ⅳ. Conclusion Improved corpus callosotomy has such advantages as little damage to the tissues,few complications and quick recovery,indicating that it is worth for further generalization.