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Kleine-Levin syndrome

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF NEUROMEDICINE

Issue:: 6

DOI:: 10.3760/cma.j.issn.1671-8925.2011.06.027

Key Word:: 过度嗜睡性障碍;强迫进食;性欲亢进;Kleine-Levin综合征;Periodic hypersomnia;Compulsive megaphagia;Hypersexuality;Kleine-Levin syndrome

Abstract： @@ 1925年神经病学家Kleine首次描述了一组症状:复发性嗜睡、行为障碍(暴食和无节制的性冲动)及精神障碍[1].1936年精神病学家Levin建议将这组症状命名为"周期性嗜睡一病态饥饿综合征"[2].1942年被重新命名为Kleine-Levin综合征(KLS)[3].1990年国际睡眠障碍分类中其被纳入复发性嗜眠症范畴[4].国内外KLS的相关研究资料一直很少,直至2005年Arnulf等[5]对既往零星报道的病例进行系统综述后才引起广泛关注.为提高对本病的识别能力,避免漏诊和误诊,本文对KLS做一系统综述.

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