Curative effect of EEG localization and microsurgery for intractable epilepsy

( views:223, downloads:0 )
Author:
YAO Shi-bin(Department of Neurosurgery,First Affiliated Hospital,PLA General Hospital,Beijing 100037,China)
LI An-min(Department of Neurosurgery,First Affiliated Hospital,PLA General Hospital,Beijing 100037,China)
LIANG Shu-li(Department of Neurosurgery,First Affiliated Hospital,PLA General Hospital,Beijing 100037,China)
ZHANG Hong-da(Department of Neurosurgery,First Affiliated Hospital,PLA General Hospital,Beijing 100037,China)
Journal Title:
CHINESE JOURNAL OF NEUROMEDICINE
Issue:
Volume 7, Issue 03, 2008
DOI:
Key Word:
Intractable epilepsy; Electroencephalography; Ambulatory EEG monitoring Electroconicogram monitoring

Abstract: Objective To explore the epileptogenic focus locating methods before and during operation and the curative effect of surgical treatment on the basis of localization. Methods Epileptogenic foci in 621 cases of intractable epilepsy were localized according to clinical manifestations and imaging findings by routine EEG (REEG), ambulatory EEG (AEEG) or video-EEG (VEEG).Different types of operations were performed based on the categories of epilepsy, the preoperatively localized foci and electrocorticogram (ECoG) monitoring results during operations. Results The follow-up ranging 0.5-4 years revealed, according to the criteria of International Antiepileptic Association,that 340 cases(54%)were completely recovered(no postoperative seizure),223 cases(36%)were improved obviously (seizure frequency was decreased by more than 75%), 37 cases (6%) were improved a little(seizure frequency was decreased by 50%-75%)and 21(3%)were not improved(seizure frequency was decreased by less than 50%): the effective rdte was 97%.No case worsened.Conclusions Preoperative integrated localization by EEG principally and intraoperative ECoG monitoring can effectively confirm the site and size of epileptogenic foci to instruct the operation and prevent complications so that the satisfactory treatment efficacy can be achieved.

  • [1]吴逊,沈鼎烈.难治性癫痫[J].中华神经科杂志,1998,3(1):4.
  • [2]梁树立.顽固性癫痫的外科治疗方法新进展[J].亚洲癫痫杂志,2002,1(1):52-58.
  • [3]徐如祥,刘智良,张新伟,等.颞叶癫痫的外科治疗及预示疗效的相关因素(143例回顾性分析)[J].第一军医大学学报,2003,23(7):663-667.
  • [4]乔慧,谭郁玲,白勤.长程脑电对癫痫外科术前定位的价值[J].中华神经外科杂志,2000,16(4):252.
  • [5]栾国明.积极稳妥地开展癫痫外科手术[J].中华神经外科杂志,2002,18(4):207-208.
  • [6]孙瑞发,赵克明,刘瑞云,等.难治性癫痫的外科手术治疗[J].现代神经疾病杂志,2003,3(1):56-57.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn