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Study on treatment of prolactinomas:a report of 684 cases
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROMEDICINE
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1671-8925.2007.07.017
- Key Word:
- 垂体泌乳素腺瘤;外科手术;药物疗法;放射疗法
Abstract： 目的 根据垂体泌乳素腺瘤患者不同的就诊目的及肿瘤大小、症状的不同,探讨适合病人个性化规范化的最佳治疗方法.方法 684例垂体泌乳素腺瘤患者根据肿瘤大小,结合症状及就诊目的,分别采取手术、药物及放疗方法,并评价不同方法的疗效.结果 369例采用手术治疗,全切除率为91%,多数为直径＞1.5 cm的肿瘤.250例药物治疗(溴隐亭)者中有189例微腺瘤患者,其症状改善率为178/189.65例γ刀治疗者中症状改善者为46例.结论 对肿瘤直径＞1.5 cm,有视力障碍者可首选手术治疗.对有生育要求的,肿瘤直径≤1.0 cm者首选药物治疗.对于肿瘤直径＜1.5 cm,未累及视神经,又不能耐受药物治疗者,γ刀治疗效果肯定.临床上应根据患者的具体情况采取个性化治疗方案.
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