Transfection and initial detection of human GAD67 gene into bone marrow stromal cells-derived neural stem cells

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Author:
MA Hong-wei()
ZHANG Ran()
HUANG Wei()
HUANG Yong-an()
XU Ru-xiang()
JIANG Xiao-dan()
LIU Zhi-liang()
ZHANG Xue()
CHEN Zhen-zhou()
GUO Ai-lin()
SU Jian()
WANG Rao()
Journal Title:
CHINESE JOURNAL OF NEUROMEDICINE
Issue:
Volume 6, Issue 03, 2007
DOI:
Key Word:

Abstract:

  • [1]Ellenberger C,Mevissen M,Doherr M,et al.Inhibitory and excitatory neurotransmitters in the cerebrospinal fluid of epileptic dogs[J].Am J Vet Res,2004,65(8):1108-1113.
  • [2]Allen NJ,Karadottir R,Attwell D.Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy[J].Pflugers Arch,2004,449(2):132-142.
  • [3]Yogeeswari P,Sriram D,Vaigundaragavendran J.The GABA shunt:an attractive and potential therapeutic target in the treatment of epileptic disorders[J].Curr Drug Metab,2005,6(2):127-139.
  • [4]Shchegel'skaia EA,Mikulinskii IuE,Revishchin AV,et al.Pluripotency of bone marrow stromal cells and perspectives of their use in cell therapy[J].Ontogenez,2003,34(3):228-235.
  • [5]刘智良,马宏伟,姚志彬,等.人类GAD67基因扩增及pEGFP-C2-GAD67真核表达载体的构建[J].中华神经医学杂志,2006,5(11):1090-1092.
  • [6]姜晓丹,徐如祥.神经干细胞培养基及其制备方法[P].中国专利,2003-01-08.
  • [7]Barker RA,Widner H.Immune problems in central nervous system cell therapy[J].NeuroRx,2004,1(4):472-481.
  • [8]Yang LY,Huang TH,Ma L.Bone marrow stromal cells express neural phenotypes in vitro and migrate in brain after transplantation in vivo[J].Biomed Environ Sci,2006,19(5):329-335.
  • [9]金澎,徐如祥,姜晓丹,等.成人骨髓源性神经干细胞的致瘤性研究[J].中华神经医学杂志,2005,4(1):10-15.
  • [10]Kalkman HO,Loetscher E.GAD (67):the link between the GABA-deficit hypothesis and the dopaminergic-and glutamatergic theories of psychosis[J].J Neural Transm,2003,110(7):803-812.
  • [11]Thompson KW,Suchomelova LM.Transplants of cells engineered to produce GABA suppress spontaneous seizures[J].Epilepsia,2004,45(1):4-12.
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