Natural course of plasma Aβ variables during normal aging and their clinical values for diagnosing Alzheimer's disease

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Author:
XU Wu-hua()
SHOJI Mikio()
MA TSUBARA Etsuro()
LIANG Rui-hua()
HE Li-chan()
ZHANG Su-ping()
Journal Title:
CHINESE JOURNAL OF NEUROMEDICINE
Issue:
Volume 4, Issue 08, 2005
DOI:
Key Word:

Abstract:

  • [1]Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease:progress and problems on the road to therapeutics[J]. Science, 2002,297(5580): 353-356.
  • [2]Demattos RB, Bales KR, Parsadanian M, et al. Plaque-associated disruption of CSF and plasma amyloid-β (Aβ) equilibrium in a mouse model of Alzheimer' s disease[J]. J Neurochem, 2002, 81 (2):229-236.
  • [3]Demattos RB, Bales KR, Cummins DJ, et al. Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer' s disease[J]. PNAS,2001, 98(15): 8850-8855.
  • [4]McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer' s disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer' s disease[J]. Neurology, 1984, 34(7): 939-944.
  • [5]Shoji M, Kanai M, Matsubara E, et al. The levels of cerebrospinal spinal Aβ40 and Aβ42 (43) are regulated age-dependently [J].Neurobiol of Aging, 2001, 22(2): 209-215.
  • [6]Kawarabayashi T, Younkin LH, Saido TC, et al. Age-dependent changes in brain, CSF, and plasma amyloid βprotein in Tg2576transgenic mouse model of Alzheimer' s disease[J]. J Neurosci, 2001,21(2): 372-381.
  • [7]Mayeux R, Honig LS, Tang MX, et al. Plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk[J]. Neurol,2003, 61(9): 1185-1190.
  • [8]Fukumoto H, Tennis M, Locascio JJ, et al. Age but not diagnosis is main predictor of plasma amyloid β-protein levels [J]. Arch Neurol,2003, 60(7): 958-964.
  • [9]Mehta PD, Pirttila T, Patrick BA, et al. Amyloid beta protein 1-40and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer's disease[J]. Neurosci Lett, 2001, 304(1-2):102-106.
  • [10]Skovronsky DM, Lee VM, Pratico D, et al. Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C[J]. J Biol Chem, 2001, 276(20):199-203.
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