Trauma-induced auditory nerve degeneration due to cerebellopontine(CP) angle manipulations:clinical and experimental experience
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROMEDICINE
- Issue:
- 1
- DOI:
- No doi available
- Key Word:
- auditory nerve;cerebellopontine angle
Abstract： In order to investigate the pathophysiologic mechanisms responsible for trauma-induced hearing disturbances due to auditory nerve degeneration, we established for the first time a rat experimental model in which auditory nerve degeneration due to compression injury of the cerebellopontine (CP) angle portion of the auditory nerve can be quantitatively evaluated. In this paper, Ⅰ demonstrate our clinical experience in CP angle surgery and some of the results of our experiments performed onthis rat experimental model. Trauma-induced hearing loss in CP angle operations has long been regarded as a sort of unavoidable "natural course"and therefore hopeless.I believe that this pessimistic view should be challenged and changed through new approaches in scientific research.
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