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Expressions of ICAM-1 and VCAM-1 associated with ischemia-reperfusion brain injury
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROMEDICINE
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1671-8925.2003.06.020
- Key Word:
- ICAM-1;VCAM-1;表达;脑缺血再灌注损伤
Abstract： 本文综述了近几年ICAM-1和VCAM-1的表达及其机制在脑缺血再灌注损伤方面的研究,认为1CAM-1和VCAM-1是与脑缺血再灌注损伤关系密切的细胞粘附分子,脑缺血再灌注损伤可导致ICAM-1及VCAM-1不同程度地表达增加,是主要通过NF-kB途径实现.有关其调控机制及其抗体的临床应用有待进一步研究.
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