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The evaluation of 1H magnetic resonance spectroscopy (1H MRS)in the diagnosis of astrocytoma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROMEDICINE
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1671-8925.2003.06.005
- Key Word:
- 星形细胞瘤;1H磁共振波谱;代谢产物
Abstract： 目的探讨质子磁共振波谱(1H Magnetic Resonance Spectroscopy,1H MRS)在星形细胞肿瘤诊断及分级中的价值.方法对MRI诊断为脑星形细胞肿瘤并经病理证实的40例患者术前行1H MRS检查,每例患者均行肿瘤区和与之相对应的健侧部位的1HMRS,以作对照研究.结果40例星形细胞瘤均表现为异常的1HMRS,主要表现为氮乙酰门氡氨酸(N-acetylaspartate,NAA)的含量下降;胆碱(choline,Cho)的含量增高,但有3例呈轻微减少改变;肌酸(creatine,Cr)总量变化不大,且无规律性;肌醇(Ins)含量表现为轻度下降,有1例升高;特别是NAA/Cho比值明显下降.结论1HMRS可提高对星形细胞瘤诊断和分级的准确性.
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