A clinical studv on surgical treatment for perirolandic epilepsy and the oredictor for good outcomes
- Author:
- No author available
- Journal Title:
- Chinese Journal of Neurosurgery
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1001-2346.2011.05.002
- Key Word:
- 中央区癫痫;功能定位;预后;手术治疗;Perirolandic epilepsy;Functional brain mapping;Prognosis;Surgical treatment
Abstract： Objective The purpose of the study was to investigate effective surgical procedure for perirolandic epilepsy and the predictor for good outcomes.Method We collected 21 subjects who underwent epilepsy surgeries consecutively in Beijing Institute of Functional Neurosurgery with the epileptogenic zone located in perirolandic areas from October 2006 to March 2008.Over 12 -month following up and Engel Ⅰ and Ⅱ taken as “good” outcomes,we analyzed the predicting factors for good outcomes.Results At the end of follow up,Engel class Ⅰ and Ⅱ were 14 cases(67％ ).Patients with lesion in MRI obtained better outcomes and patients with focal cortex dysplasia(FCD) pathology obtained worse outcomes regarding the rate of Engel class Ⅰ + Ⅱ( P ＜ 0.05).There were no serious functional deficits.Conclusions Surgical resection of epileptogenic zone for periroladic epilepsy can achieve good outcomes.Patients with lesion in MRI predicted better outcomes and FCD pathology predicted worse outcome.
- [1]魏新亭,保建基,孙红卫,等.大脑功能区皮质下占位性病变的手术治疗[J].2006,(12).
- [2]楼美清,卢亦成,丁学华,等.中央沟附近胶质瘤的诊断和手术治疗[J].2004,(3).
- [3]张忠,江涛,谢坚,等.唤醒麻醉和术中功能定位切除语言区胶质瘤[J].2007,(9).
- [4]倪端宇,蔡立新,张国君,等.皮层电刺激定位功能区的有效刺激参数研究[J].2011,(1).
- [5]Nishida N,Taki J,Ohara S,etc.Evidence for a wide distribution of negative motor areas in the perirolandic cortex.[J].2006,117(1).
- [6]Palmini A.The concept of the epileptogenic zone: a modern look at Penfield and Jasper's views on the role of interictal spikes.[J].2006,8(Suppl.2).
- [7]Ridding MC,delaide.edu.au,McKay DR,etc.Changes in corticomotor representations induced by prolonged peripheral nerve stimulation in humans.[J].2001,112(8).
- [8]姚一,谭启富,张小斌,等.涉及中央区难治性癫痫的外科治疗[J].2008,005 (3).
- [9]Gyimesi C,Nayel M,Pannek H,etc.Outcome of extratemporal epilepsy surgery experience of a single center.[J].2008,63(3).
- [10]GuoJun Z,Liang,DuanYu N.Surgery for perirolandic epilepsy: Epileptogenic cortex resection guided by chronic intracranial electroencephalography and electric cortical stimulation mapping.[J].2010,112(2).
- [11]遇涛,张国君,于爱红,等.语言功能区定位与近语言功能区癫（癎）灶切除（附11例分析）[J].2009,(11).