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Analysis on 11 cases of cerebellar gangliogliomas

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF NEUROSURGERY
Issue:
7
DOI:
10.3760/cma.j.issn.1001-2346.2010.07.005
Key Word:
小脑;神经节胶质细胞瘤;显微外科手术;预后;Cerebellum;Ganglioglioma;Microsurgery;Prognosis

Abstract: Objective Ganglioglioma ( GG) is a less common primary neoplastic disease of the central nervous system that is typically located supratentorially. The objective of the study is to discuss the clinical characteristics, microsurgical treatment and prognosis of the cerebellar GGs. Method The hospital data of 11 patients who had undergone microsurgery and were pathologically diagnosed as cerebellar GGs were reviewed. Results Among 11 patients, 6 located in the cerebellum and 5 located in thevermiform process of cerebellum respectively. The main clinical presentations were intracranial hypertension and ataxia. The mean age at presentation was 25 years. The operations consisted of total resection in six, subtotal resection in 5. There was no increased neurological deficits except for one meningitis, and no postoperative death. Ten patients were followed up with a mean of 3 years, of which 9 lived a normal life expect for one patient died of diabetes mellitus complication. There was one patient with recurrent tumors in the series. Conclusions Preoperative diagnosis of cerebellar GGs may be presumed on the basis of case history and neuroimaging examinations. Its precise diagnosis mainly depends on histopathology. Surgical resection is the principal treatment for cerebellar GGs and can get the good prognosis.

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