Abstract： Objective To assess the feasibility and clinical application for integration of preoperative BOLD and low-field iMRI in giioma surgery involving motor cortex.Methods 48 patients with glioma involving the motor cortex were randomly divided into trial or control group.In the trail group,the preoperative BOLD was merged into the image from low-field iMRI for neuronavigation.In the control group,the preoperative BOLD Was merged into preoperative high-field MRI for neuronavigation.The IOM were performed to evaluate the effeetiveness of BOLD.The motor function of extremities Was examined before and after operation.Results In the trail group.the sensitivity of BOLD was 73.3% and specificity Was 83.3% while it was 75.5% and 81.2% in the control group respectively.The lesions were completely resected in 85.1% of the trial group.and 77.8% of the control group(P<0.05).80.8% of the patients in trial group did not suffer surgery-induced paralysis.while the rate in the control group WaS 83.3% (P >0.05).Conclusions The integration of BOLD and iMRl is feasible to raise the total removal rate and decrease the rate of aggravation of motor function in glioma surgery involving motor cortex.