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Correlation of pathological subtypes and surgical outcomes in intractable epilepsy due to focal cortical dysplasia

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF NEUROSURGERY
Issue:
3
DOI:
10.3760/cma.j.issn.1001-2346.2010.03.002
Key Word:
局灶性脑皮质发育不良;组织学;外科手术;癫痫;Focal cortical dysplasia;Histology;Surgical procedures,operative;Epilepsy

Abstract: Objective To explore the correlation of pathological subtypes and surgical outcomes in intractable epilepsy due to focal cortical dysplasia(FCD).Method The data of the pathological subtypes and surgical outcomes in 54 patients of FCD proved by pathological examination were reviewed retrospectively.The relationship between pathological subtypes and surgical outcomes was analyzed.Results Of 54 cases,24 were classified as the mild group(FCD Ⅰ A),30 the severe group(FCD Ⅰ B + Ⅱ A+ Ⅱ B).The effective rate of FCD surgery was 96% in the mild group,while 70% in the severe group,with the total effective rate 82%.Conclusions The severer the histological lesion of FCD,the worse the surgical outcome.FCD may be one of the important factors influencing the postoperative outcomes of intractable epilepsy.

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