Abstract： Objective To summarize the experiences in endovascular stenting for vertebrobasilar artery stenosis, and to discuss its indications, technique, perioperative management, risk factor and postoperative effect. Methods Between January 2004 and July 2008, the transluminalstent-assisted angioplasty was performed in 95 patients with symptomatic vertebrobasilar artery stenosis. Results The locations of the stenoses were originated at vertebral artery 21 cases, vertebral artery carotid segment 3 cases, vertebral artery intracranial segment 16 cases, joint of vertebral and basilar artery 15 cases, basilar artery 36 cases, posterior cerebral artery P2 segment 4 cases, All stenoses were more than 50%. The successful rate of stent implantation was 97% (92/95) without any serious complications. The degree of stenosis was significantly improved from 76. 1% to 9.2%. During the follow-up, 88 cases there was no neurologic complication. Conclusions Preliminary results suggest that transluminal stent-assisted angioplasty in the treatment of verte-brobasilar ischemia to be a safe and effective. Long-term angiographic and clinical follow-up for monitoring a larger number of patients is needed.