Abstract: Objective To explore the methods and effectiveness of neurosurgical management of spastic cerebral palsy. Method Among 351 patients of spastic cerebral palsy(aged from 2 to 14 years, 4.8 in average), the treatment includes 26 cervicothoracic selective posterior rhizotomy (SPR), 109 lumbosacral SPR; 216 selective peripheral neurotomy (SPN) include 92 single neural trunk neurotomies and 124 multiple neural trunk neurotomies. Results Following-up period was from 6 to 31 months (means 17.8 months). The spasm was improved by 82.7% and 91.4% in cervicothoracic SPR and lumbosacral SPR. The movement was improved by 83.7% and 72.5% in upper and lower limbs respectively. In peripheral neurotomy, the spasm was improved by 67.4% and 92.7% in upper and lower limbs. The movement was improved by 54.9% in upper limbs and 84.3% in lower limbs. Conclusions Neurosurgical management is an effective and safe method for treatment of spastic cerebral palsy, offers a chance for effectual rehabilitation. The preoperational evaluation, the suitable operation decision and the understanding of microsurgical techniques are the key to gain good effects and prevent complication.