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Endoscopic endonasal transsphenoidal surgery for pituitary adenoma

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF NEUROSURGERY
Issue:
5
DOI:
10.3321/j.issn:1001-2346.2008.05.004
Key Word:
垂体,腺瘤;内镜;蝶窦;外科手术;Pituitary,adenoma;Endoscope;Sphenoid sinus;Surgical procedures,operative

Abstract: Objective To describe the technique of endoscopic endonasal transsphenoidal surgery for treatment of pituitary adenoma.Method Clinical data of 100 patients with pituitary adenoma that underwent endoscopic endonasal transsphenoidal surgery between September 2003 and March 2006 was analyzed.30 patients had microadenomas,35 patients macroadenomas,and 35 patients gigantic adenomas.68 patients had hormone secreting adenomas.32 had non-functioning adenomas.All operations were performed through a nostril using pure rigid endoscopes.Results Among the 100 patients,total resection was in 93 patients,subtotal resection in 7 patients.32 patients developed postoperative diabetes insipidus,5 developed CSF leakage.All patients were followed by mean 28 months,residual tumor was found in 10 patients.Among 12 patients with tumor recurrence,10 performed second endoscopic endonasal surgery and 2 underwent transcranial surgery.18 patients were treated with gamma knife surgery and 11 patients were treated with a course of bromocriptine therapy.Conclusions Endoscopic endonasal transsphenoidal surgery is a mini-invasive surgical technique for treatment of pituitary adenomas.

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