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Pituitary hyperplasia in children with primary hypothyroidism: four cases report and review of literatures
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 6
- DOI:
- 10.3760/j.issn:1001-2346.2006.06.002
- Key Word:
- 甲状腺功能减退;垂体增生;甲状腺素
Abstract： 目的探讨儿童甲状腺功能减退导致垂体增生的临床特点、发病机制和治疗.方法报告4例儿童继发于甲状腺功能减退的垂体增生病例,并结合文献进行分析.结果 4例儿童均表现为TSH和PRL增高及FT3和FT4的减少、垂体增大.CT和MRI冠状扫描显示垂体高度1.6～2.3cm,3例服用甲状腺素后垂体肿物消失及内分泌紊乱恢复正常;另1例手术行肿物大部切除,病理报告"垂体细胞瘤样增生",服用甲状腺素及强的松,3个月后复查MRI显示为部分性空蝶鞍.结论当患儿有TSH和PRL增高伴垂体增大时,首先应考虑为"垂体增生",仅服用甲状腺素治疗即可获得痊愈.
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