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Combined fractionated stereotactic radiotherapy and conventional radiotherapy in patients with high-grade gliomas
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1001-2346.2006.05.004
- Key Word:
- 高分级脑胶质瘤;放射治疗;立体定向
Abstract： 目的采用立体定向放疗与常规放疗结合治疗高分级脑胶质瘤,分析其疗效,探讨其影响预后的因素.方法自1998年12月至2005年1月用立体定向放疗与常规放疗结合的方法治疗高分级脑胶质瘤106例.立体定向放疗针对GTV追加剂量,每次5～7Gy,共计5～7次,常规放疗主要针对亚临床病变,一般剂量为50Gy.寿命表法统计生存率.结果本组病例1、3年生存率分别为66.2%和27.0%.Ⅲ级胶质瘤较Ⅳ级的患者预后好,预后与年龄、肿瘤部位和治疗剂量等其他因素无关.结论立体定向放疗加常规放疗治疗高分级脑胶质瘤既发挥了放射物理剂量分布的优点,又符合放射生物学原则,较以往治疗提高了患者的生存机会.
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