You Position: Home > Paper
Ultrastructure of stereotactic biopsy specimens from peritumoral edema area in astrocytomas
( views:186, downloads:12 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1001-2346.2006.02.009
- Key Word:
- 星形细胞瘤;瘤周脑水肿;立体定向活检;超微结构
Abstract： 目的探讨星形细胞瘤瘤周脑水肿的发生机制.方法对15例星形细胞瘤瘤周脑水肿的宽度进行分级:一级0～20mm、二级21～40mm、三级＞40mm.结合CT平扫及增强扫描的影像,应用立体定向技术,对15例星形细胞瘤瘤体、瘤周水肿区及正常脑组织的活检标本进行电镜观察比较.结果CT增强扫描可强化,瘤周脑水肿明显的病人,其瘤体及瘤周水肿区毛细血管超微结构均有不同程度的改变.毛细血管的分布和结构变化,影响着瘤周水肿区的形态,瘤体毛细血管的明显异常,出现于大范围瘤周水肿区的病例.CT增强扫描无强化,瘤周脑水肿不明显的病人,毛细血管超微结构与正常脑组织相似.结论伴有明显瘤周脑水肿的星形细胞瘤,其瘤体及瘤周水肿区毛细血管超微结构均有不同程度的改变,而瘤周水肿的产生,是瘤体及瘤周水肿区毛细血管超微结构改变共同作用的结果.
- [1]Pronin, I. N.,Holodny, A. I.,Petraikin, A. V..MRI of high-grade glial tumors: correlation between the degree of contrast enhancement and the volume of surrounding edema[J].1997,39(5).
- [2]K A, Hossmann,K, Seo,J, Szymas,etc.Quantitative analysis of experimental peritumoral edema in cats.[J].1990,52.
- [3]Neuwelt EA,Specht HD,Howieson J,etc.Osmotic blood-brain barrier modification: clinical documentation by enhanced CT scanning and\/or radionuclide brain scanning[J].1983.
- [4]Yamada Kazuo,Ushio Yukitaka,Hayakawa Toru,etc.Effects of methylprednisolone on peritumoral brain edema[J].1983.
- [5]O J, Castejón.Ultrastructural alterations of human cortical capillary basement membrane in perifocal brain edema.[J].1988,20.