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The treatment of trigeminal neuralgia using Gamma knife with double targets
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1001-2346.2005.04.009
- Key Word:
- 原发性三叉神经痛;伽玛刀;双靶点
Abstract： 目的探索使用双靶点来改进伽玛刀治疗三叉神经痛的技术,提高有效率,减少复发率.方法55例病人接受了伽玛刀双靶点治疗,9例失随访.87%的病人术前有手术史.一个靶点放在三叉神经根近桥脑处,另一个放在近半月神经节处,中心剂量84～90Gy,周边剂量42～45Gy,桥脑临界剂量20Gy.结果随访4-72个月(平均30个月).术后疼痛消失时间为2h-16个月(平均4个月).按疼痛缓解评分,在随访时点,总有效率为95.7%,面部感觉异常等并发症的发生率为10.8%.经统计学分析,某些因素与疗效相关.结论采用伽玛刀双靶点治疗三叉神经痛,因增加了辐射容量,比单靶点的成功率高、复发率低,并发症发生率与双靶点相近.特别值得一提的是,当病人术前有沿三叉神经注射史的,双靶点治疗比单靶点治疗的优越性更明显.
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