You Position: Home > Paper
Anatomical study of relative targets MRI localization in Parkinson's disease
( views:320, downloads:147 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1001-2346.2004.04.005
- Key Word:
- 帕金森病;立体定向;磁共振成像;脑图谱;靶点
Abstract： 目的探讨MRI定位帕金森病手术相关靶点的准确性和实用性.方法采用T1序列对76例活体人脑前后连合间径(LI)在MRI上的长度进行测量;采用自旋回波翻转恢复序列和T2序列对10名健康人以LI为扫描基线,行3mm层厚、无间距的矢状位、轴位和冠状位头部MRI扫描,分析帕金森病手术相关靶点的MRI位置、影像学特点.结果 76例活体人脑MRI上的LI平均长度为22.90±1.30mm;丘脑底核(STN)和苍白球内侧部(GPi)在MRI上清晰显示,其靶点坐标STN为中线旁开12.01±1.25mm,原点后0.62±1.07mm,AC-PC平面下3mm;GPi为中线旁开19.99±1.48mm,原点前3mm,AC-PC平面下3.20±1.24mm.腹内侧中间核(Vim)为MRI不可见靶点,但可根据AC、PC、AC-PC连线和三脑室进行直观、简便的推算.结论 MRI可直接、准确地显示脑内一些帕金森病手术相关靶点.
- [1]张宇清,张国君,李勇杰.中西方人脑内连合间径的比较[J].2002,(1).
- [2]Atkinson JD,Pike GB,Bertrand G,etc.Optimal location of thalamotomy lesions for tremor associated with Parkinson disease: a probabilistic analysis based on postoperative magnetic resonance imaging and an integrated digital atlas.[J].2002,96(5).
- [3]Kondziolka D,Kim YS,Lunsford LD,etc.Outcomes after stereotactically guided pallidotomy for advanced Parkinson's disease.[J].1999,90(2).
- [4]姚家庆,戴蘅茹著.人脑立体定位应用解剖[M].1992.
- [5]Richter EO,Hoque T,Halliday W,etc.Determining the position and size of the subthalamic nucleus based on magnetic resonance imaging results in patients with advanced Parkinson disease.[J].2004,100(3).
- [6]Teijeiro Amador J,Maragoto C,Lopez Flores G,etc.Anatomic and neurophysiological methods for the targeting and lesioning of the subthalamic nucleus: Cuban experience and review.[J].2003,52(4).
- [7]Hidehiro, Hirabayashi,Magnus, Tengvar,Marwan I, Hariz.Stereotactic imaging of the pallidal target.[J].2002,17 Suppl 3.