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Deep brain stimulation of the subthalamic nucleus in idiopathic Parkinsons disease
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1001-2346.2002.01.002
- Key Word:
- 帕金森病;脑深部电刺激;丘脑底核
Abstract： 目的探讨脑深部电刺激(DBS)对原发帕金森病(PD)的治疗作用及手术方法.方法应用微电极导向技术和手术计划系统进行靶点定位,对20例PD病人的丘脑底核(STN)进行电极植入,术后至少6个月的评价和随访.结果 15例单侧和5例双侧STN的DBS术后病人肢体僵直、震颤和运动迟缓等症状改善明显,术前术后UPDRS运动评分和日常生活能力评分均有显著下降(P＜0.01),服药量也有不同程度的减少,无严重及永久并发症. 结论 STN的DBS手术治疗PD,对症状改善非常全面,可通过参数调整达到最佳治疗效果,服药量明显减少,是一种安全、有效的治疗方法.
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