Prognosis of combined liver-kidney transplantation

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Author:
SUN Li-ying(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
ZHU Zhi-jun(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
LIU Yi-he(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
ZHENG Hong(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
DENG Yong-lin(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
PAN Cheng(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
SHEN Zhong-yang(Organ Transplantation Center, Tianjin First Center Hospital, Tianjin 300192, China)
Journal Title:
Chinese Journal of Organ Transplantation
Issue:
Volume 33, Issue 09, 2012
DOI:
10.3760/cma.j.issn.0254-1785.2012.09.005
Key Word:
Liver transplantation;Kidney transplantation;Combined transplantation;Complication;Graft survival;Survival rate

Abstract: Objective To analyze the curative effects and survival results of combined liver kidney transplantation (CLKT).Methods From 2002 to 2011,the clinical data of 36 Chinese patients who underwent CLKT were retrospectively analyzed in our centre.The age of recipients was 47.4 ±13.1 years.Four patients had undergone liver transplantation and 7 patients kidney transplantations before CLKT, respectively. The complications and the survival were analyzed. Results The survival patients were followed up for 47.9 months (29.1 - 115.7).The cumulative 1-,3 and 5-year patient survival rate was 88.7%,85.4% and 81.4%; The 1,3- and 5-year survival rate of liver graft was 79.8%,76.3% and 72.3%; The 1-,3- and 5 year survival rate of kidney graft was 85.7%,82.4% and 78.2%.Three patients underwent liver re-transplantation due to severe biliary complications,and one patient kidney re-transplantation due to renal allograft dysfunction.Conclusion CLKT is a effective treatment for end-stage liver disease with renal insufficiency and achieves excellent results.

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