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An initially clinical study of pneumocystis carinii pneumonia during early stage after orthotopic liver transplantation
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 12
- DOI:
- 10.3760/cma.j.issn.0254-1785.2006.12.003
- Key Word:
- 肺炎,肺囊虫性;肝移植
Abstract： 目的 探讨原位肝移植(OLT)术后早期合并卡氏肺孢子虫肺炎(PCP)的病因、诊断和治疗.方法 回顾276例原位肝移植患者的术后资料,并对6例合并PCP患者的临床资料进行分析总结.结果 276例肝移植患者术后PCP发病率为2.17%(6例),平均发病时间为(11.17±2.50)d,主要表现为不易纠正的低氧血症.经临床症状、胸部X片、肺部CT、痰卡氏肺孢子虫聚合酶链反应(PCR)检测及镜检卡氏肺孢子虫包囊明确诊断.确诊后给予复方新诺明(SMZco)治疗,同时合理调整免疫抑制方案.经治疗,5例患者治愈出院,1例死于感染性休克.结论 原位肝移植术后早期可并发PCP,提高对PCP发病的认识、及时诊断与治疗是影响预后的关键.
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