You Position: Home > Paper
Early diagnosis and management of acute respiratory distress syndrome caused by cytomegalovirus pneumonia after liver transplantation
( views:319, downloads:36 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 10
- DOI:
- 10.3760/cma.j.issn.0254-1785.2005.10.001
- Key Word:
- 肝移植;巨细胞病毒;肺炎;呼吸窘迫综合征
Abstract： 目的探讨肝移植术后巨细胞病毒性肺炎合并呼吸窘迫综合征的早期诊断和处理.方法回顾性分析2001年4月至2004年5月期间8例肝移植患者术后出现巨细胞病毒性肺炎合并呼吸窘迫综合征的临床资料.8例患者均给予更昔洛韦5 mg/kg静脉滴注,2次/d;减少他克莫司(FK506)或环孢素A(CsA)1/3～1/2的用量,停用霉酚酸酯(MMF)和泼尼松;使用呼吸机辅助呼吸,同时加强支持治疗.结果8例患者中5例痊愈,3例死亡.无1例发生急性排斥反应.结论胸部X线、CT检查及临床表现是早期诊断的关键.抗巨细胞病毒治疗、调整免疫抑制剂用量、使用呼吸机辅助呼吸及有效的营养支持均是改善肝移植术后巨细胞病毒性肺炎合并呼吸窘迫综合征的有力措施.
- [1]Benita Zweygberg Wirgart,Kerstin Claesson,Britt-Marie Eriksson,etc.Cytomegalovirus (CMV) DNA amplification from plasma compared with CMV pp65 antigen (ppUL83) detection in leukocytes for early diagnosis of symptomatic CMV infection in kidney transplant patients[J].1996,7(2).
- [2]Xiol X,Lama C,Figueras J,etc.Pretransplantation risk factors for graft loss after liver transplantation in cirrhotic patients; effect of cytomegalovirus serologic status.[J].2004,17(3).
- [3]Mulligan DC,Post AB,Bush W.Cost analysis of four strategies for prevention of CMV infection in liver transplant recipients.[J].1998,30(5).
- [4]Keyes L,Wannstedt C,Gayowski T,etc.Impact of evolving trends in recipient and donor characteristics on cytomegalovirus infection in liver transplant recipients.[J].2004,77(1).
- [5]van den Berg A. P.,van Son W. J.,Janssen R. A. J.,etc.Recovery from Cytomegalovirus Infection Is Associated with Activation of Peripheral Blood Lymphocytes[J].1992.