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Molercular adsorbent recycling system treating acute liver failure:a bridge to liver transplantation
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.0254-1785.2004.03.003
- Key Word:
- 分子吸附循环系统;肝移植;肝功能衰竭,急性;肝,人工
Abstract： 目的探讨应用分子吸附循环系统结合肝移植治疗急性肝功能衰竭的效果.方法 8例急性肝功能衰竭患者(7例原发病为乙型肝炎后肝硬化,1例为Wilson病)在等待肝移植期间经分子吸附循环系统治疗3～7次,所有患者均接受同种异体改良背驮式肝移植术.结果患者等待供肝时间8～30 d,平均13 d,所有患者均顺利渡过围手术期,痊愈出院.应用分子吸附循环系统治疗后,患者的血清丙氨酸转氨酶、天冬氨酸转氨酶及总胆红素水平明显下降(P＜0.01),但凝血功能的改善不明显.结论分子吸附循环系统可暂时替代肝脏的部分功能,帮助急性肝功能衰竭患者顺利渡过肝移植等待期.
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