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Liver retransplantation:report of 5 cases and review of literature
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.0254-1785.2004.01.001
- Key Word:
- 肝移植;再手术
Abstract： 目的总结再次肝移植的临床经验.方法对5例男性患者施行再次肝移植,再次肝移植的原因分别为原发性移植肝无功能(1例)、急性排斥反应(1例)、慢性排斥反应并胆道感染(1例)以及胆道缺血并感染(2例).供肝植入均采用改良背驮式原位肝移植术.术后免疫抑制治疗采用达利珠单抗、甲泼尼龙及他克莫司联合用药,必要时加用霉酚酸酯.结果 3例治愈,已分别存活11个月、5个月和1个月,2例分别于术后第8 d、第10 d死亡,1例死于多器官感染及功能衰竭,1例死于心力衰竭.术后并发症有腹腔出血、多器官感染、胆道感染及切口感染等.结论再次肝移植是移植肝功能衰竭的有效治疗方法,适应证及手术时机的正确把握、围手术期的严密监测和正确处理是提高再次肝移植患者存活率的关键.
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