You Position: Home > Paper
Detection of sensitization to HLA antigens after liver transplantation
( views:196, downloads:20 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.0254-1785.2003.05.104
- Key Word:
- 肝移植;群体反应性抗体;免疫法;移植物排斥
Abstract： 目的探讨肝移植受者致敏与移植物功能的关系.方法采用酶联免疫吸附法(ELISA)对15例患者肝移植前后的群体反应性抗体(PRA)进行动态监测.结果 15例患者肝功能的主要指标,包括丙氨酸转氨酶、总胆红素、直接胆红素等大多在术后1周内恢复正常.15例中有1例术前中度致敏,术后发生轻度排斥反应1次,经治疗后逆转,其PRA在观察期内一直保持阳性.另外14例受者移植前、后PRA均阴性(PRA＜10 %),其中1例发生排斥反应1次,但PRA仍保持阴性.结论肝移植受者的致敏状态与术后的排斥反应密切相关.
- [1]贾保祥,武俊杰,田野,等.群体反应性抗体在肾移植中的意义[J].2000,(4).
- [2]Christiaans MH,van-Hooff JP,Nieman F,etc.Donor-specific antibodies after transplantation by flow cytometry: relative change in fluorescence ratio most sensitive risk factor for graft survival.[J].1998,65(3).
- [3].Stock Market Returns and Consumption[J].2020,75(6).
- [4]McKenna RM,Takemoto SK,Terasaki PI.Anti-HLA antibodies after solid organ transplantation.[J].2000,69(3).
- [5]Mizuta K,Kawarasaki H,Imamura H,etc.Risk factors for acute rejection in pediatric living related liver transplantation: the impact of HLA matching.[J].2001,7(9).
- [6]Ramón Charco,Victor Vargas,Joaquim Balsells,etc.Influence of anti-HLA antibodies and positive T-lymphocytotoxic crossmatch on survival and graft rejection in human liver transplantation[J].1996,24(4).
- [7]A J, Matas,K J, Gillingham,B A, Elick,etc.Risk factors for prolonged hospitalization after kidney transplants.[J].1997,11(4).