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Establishment of combined liver-kidney transplantation model in rats
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.0254-1785.2003.01.106
- Key Word:
- 肝;肾;移植;大鼠;模型,生物学
Abstract： 目的建立大鼠肝、肾联合移植模型.方法选用Wistar大鼠,以4℃乳酸钠林格注射液经门静脉和腹主动脉对供肝和供肾进行原位灌洗.移植时除肝上下腔静脉缝合外,其余血管重建均采用袖套式吻合,将供肾附带的一段腹主动脉修剪成椭圆状,方便操作,并满足对等口径吻合,供肾输尿管拖出种入膀胱.结果共完成35次大鼠原位肝、肾联合移植手术,其中后20次手术成功率为90%,最长存活时间超过5个月.结论该模型可运用于移植相关研究.
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- [3]胡浩,陈易人,李纲.100例大鼠原位肝移植[J].1999,(3).