Abstract： Objective　To study the clinica l and histopathologic characters of recurrent and de novo IgA nephropathy (IgAN) following cadaveric kidney transplantation, and investigate the prognosis. Method　Three patients were diagnosed as having transplan t IgAN from 36 patients with abnormal renal function (proteinuria, hematuria or/ and elevated creatinine) by renal graft biopsy and histopathologic analysis . The patients were treated with dipyridamole, low dose warfarin and tripterygium wif ordii and the therapeutic effects were observed. Results　Three patients were respectively diagnosed as havi ng de novo/recurrent membrano-preliferative IgAN (lesion of grade Ⅲ) with mode rate chronic allograft nephropathy at 30th month postoperatively, recurrent mesa ngial proliferative IgAN (grade Ⅱ) with mild chronic allograft nephropathy at 1 8th month postoperatively and de novo/recurrent mesangial proliferative IgAN (gr adeⅡ) with mild chronic allograft nephropathy at 14th month postoperatively. Al l of then were treated with dipyridamole, low dose warfarin and tripterygium wif ordii for 24 months, and unchanged basic immunosuppressive regimens (including C sA, MMF or Aza and Pred). The 3 patients kept a stable serum creatinie, improved macroscopic hematuria, and some amount of proteinuria during the treatment, but the first one with membrano-preliferative IgAN had elevated serum creatinine ( from 120-150 μmol/L up to 180-200 μmol/L) at 30th month maintenance of the treatment (60 months postoperation). Conclusions　Recurrent or de novo IgAN in renal allograft occurred quickly, efficacious treatment had been not searched out yet, and progn osis had a close relationship with degree of histopathologic lesion, classifica tion of IgAN.