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The value of biopsy in diagnosis and differentiate diagnosis of human renal allo graft impairment

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF ORGAN TRANSPLANTATION
Issue:
1
DOI:
10.3760/cma.j.issn.0254-1785.2001.01.102
Key Word:
肾移植;活组织检查;诊断

Abstract: Objective  To investigate the relation between clinical diagnosis and histologic lesion in renal allograft patients who received graft biopsies. Method 158 cases undergoing renal allograft biopsies fro m June 1996 to Dec. 1998 were analyzed retrospectively. Results Among the 158 cases, acute rejection occurred in 5 5 cases (34.8 %), renal allograft change in 35 cases (22.2 %), borderl ine lesion in 32 cases (20.2 %), chronic rejection in 13 cases (8.3 % ), mesangial proliferative lesion in 13 cases (8.3 %), acute tubular necros is in 6 cases (3.8 %), glomerular crescents formation in 1 case (0.6? %), HUS in 1 case (0.6 %), endocappillary proliferative lesion in 1 case ( 0.6 %). The level of CsA in plasma had no relation with the occurrence of a cute rejection. The difference between clinical and histological diagnosis were encountered in some patients. Conclusions The renal biops y might be essential for establishing the correct diagnosis of renal allograft d y sfunction and so selecting the appropriate management.

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