Abstract： Objectives To establish standard cervical heart transplantation in rodents that was widely used abroad and introduce its application in golden hamster-rat xenotransplantation.Methods The innominate artery and the pulmonary artery of the donor heart were anastomosed with the right common carotid artery and the external jugular vein of the recipient respectively by using end-to-end suture technique.Results There was no operative death in the whole group,and the mean survival of golden hamster-rat cervical heart xenografts was(4.0±0.8)days(n=27).Conclusions Some limitations in abdominal heart transplantation have been overcome in the cervical model.This model owns some specific applicable fields.It could be widely introduced to the internal users.