Abstract: 47 patients with positive HBsAg and 10 patients with positive anti-HCV of 444 ca-daveric kidney recipients were observed in terms of morbidity of chronic liver disease(CLD)and mortality of recipients and compared with recipients without HBV and HCV.Our results showed that morbidity of CLD was higher in patients with positive HBsAg and anti-HCV than in patients without HBV and HCV infection(36.1%,50% vs 7.7%,P<0.01)and one-year survival of graft/patient showed no significant differences among 3 groups.The 3-year survival of patients with positive HBsAg and anti-HCV was significantly lower than patients without HBV and HCV (P<0.05)and patients with virus infection had much higher rate of death due to hepatic failure.It is concluded that the virus would finally lead to the hepatic failure.