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Topical imiquimod in the treatnent of bowenoid papulosis: a retrospective study
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DERMATOLOGY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:0412-4030.2007.02.005
- Key Word:
- 鲍恩样丘疹病;治疗;咪喹莫特
Abstract： 目的 探讨5%咪喹莫特乳膏治疗鲍恩样丘疹病(BP)的疗效和对复发的影响.方法 回顾性分析39例鲍恩样丘疹病患者,第一组15例,单纯外用5%咪喹莫特乳膏,每周3次,疗程8周.第二组12例,应用CO2激光治疗.第三组12例,CO2激光联合5%咪喹莫特乳膏治疗.三组随访时间均为3个月.结果 第一组33.33%(5/15)的患者获得痊愈,无1例复发,不良反应主要表现为红斑、水肿、糜烂和疼痛,无系统不良反应.第二组CO2激光治疗后,12例全部痊愈,但66.66%(8/12)患者复发.第三组治疗后12例痊愈,仅25%(3/12)患者复发.结论 5%咪喹莫特乳膏是治疗鲍恩样丘疹病的有效药物,尤其是对皮损较小者,疗效好、复发率低.对于肥厚性和/或伴有轻度疣状损害者,CO2激光治疗后联合5%咪喹莫特乳膏可降低复发率.
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