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Expression of cysteinyl leukotriene receptors in the skin lesions of patients with subacute eczema and psoriasis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DERMATOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:0412-4030.2006.11.003
- Key Word:
- 湿疹;银屑病;受体,白三烯
Abstract： 目的 探讨湿疹和银屑病患者皮损中半胱氨酰白三烯受体CysLTR1和CysLTR2的临床意义.方法 免疫组化SP法分别检测10例亚急性湿疹和20例寻常性银屑病患者皮损中CysLTR1和CysLTR2的表达,并以外科手术中相应部位皮肤组织作为对照.结果 银屑病与湿疹患者皮损中CysLTR1和CysLTR2的表达显著高于正常对照,其阳性细胞主要位于表皮、皮脂腺、毛囊、汗腺、平滑肌及血管壁等;3组中CysLTR1和CysLTR2两型受体间的分布及表达强弱差异无统计学意义.结论 人皮肤组织中同时存在CysLTR1和CysLTR2的表达,银屑病与湿疹患者皮损中CysLTR1和CysLTR2的表达增强.
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