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Topical 5-aminolaevulinic acid-photodynamic therapy in the treatment of precancerous changes and carcinoma of the skin in situ
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DERMATOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:0412-4030.2006.03.006
- Key Word:
- 氨基酮戊酸;角化病;增殖性红斑;Bowen病
Abstract： 目的探讨5-氨基酮戊酸光动力疗法(ALA-PDT)治疗皮肤癌前病变和皮肤原位癌的疗效.方法对15例光线性角化病、3例Queyrat增生性红斑和8例Bowen病患者进行ALA-PDT治疗.结果15例光线性角化病患者的17个皮损获得完全缓解,2例复发,复发率13.33%;3例Queyrat增生性红斑除1例无效外,另2例患者的皮损获完全缓解,无复发;8例Bowen病除1例获得部分缓解外,其他7例完全缓解,1例复发.结论ALA-PDT是一种疗效好、无明显痛苦、无瘢痕形成、复发率低、美容效果好的治疗皮肤癌前病变和皮肤原位癌的新疗法;特别适合于头面部及外生殖器部位的多发性、较大面积皮损.
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