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A Study on Infection and Colonization of Mycoplasma genitalium and Ureaplasma urealyticum in Different Male Populations
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DERMATOLOGY
- Issue:
- 10
- DOI:
- 10.3760/j.issn:0412-4030.2005.10.002
- Key Word:
- 支原体属;尿素支原体,尿素分解;尿道炎;同性恋,男性
Abstract： 目的了解生殖支原体及解脲脲原体在男性不同人群中的流行状况,分析生殖支原体及解脲脲原体与男性非淋菌性尿道炎的相关性.方法病例对照研究结合横断面研究,采集性病门诊非淋菌性尿道炎患者、性病门诊无尿道炎的就诊者、男男性接触者及健康体检者4组人群的尿道拭子标本,运用培养法和套式PCR法检测解脲脲原体,套式PCR和产物DNA测序检测生殖支原体.结果生殖支原体检出率非淋菌性尿道炎患者组为2 5.0%,无尿道炎的就诊者组6.4%,男男性接触者组5.5%,健康体检者组未检出.各组与健康体检者组比较差异均有统计学意义,而非淋菌性尿道炎患者与无尿道炎的就诊者、非淋菌性尿道炎患者与男男性接触者比较,P均＜0.01,无尿道炎的就诊者与男男性接触者比较,P＞0.05.多因素回归分析发现,尿道炎与生殖支原体阳性率显著相关,P=0.004,OR=6.754,95%CI 1.833～24.893.解脲脲原体PCR阳性率在非淋菌性尿道炎患者、无尿道炎的就诊者、健康体检者组间差异无统计学意义.男男性接触者组的解脲脲原体阳性率明显低于其他三组.结论生殖支原体与非淋菌性尿道炎高度相关,男性高危性行为人群中生殖支原体的感染率较普通人群高.解脲脲原体定植在男性非淋菌性尿道炎患者、性行为高危人群及普通人群间无差异,与非淋菌性尿道炎无相关性.
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