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Erythema Annulare as the First Presentation in T-Lymphoblastic Lymphoma: A Case Report
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DERMATOLOGY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:0412-4030.2003.02.003
- Key Word:
- 淋巴母细胞,淋巴瘤;红斑
Abstract： 目的报告一例罕见的以环形红斑为初发表现的成人T淋巴母细胞性淋巴瘤.方法对其临床、组织病理、免疫组化、分子生物学和各种特殊的实验室检查进行研究.结果颈部、腹股沟肿大数10个淋巴结,全身百余个环形红斑.胸部CT示:前上纵隔占位性淋巴瘤表现.胸水中找到异形细胞.骨髓片示:淋巴瘤累及骨髓.外周血中未发现瘤细胞.淋巴结结构破坏,瘤细胞弥漫分布,呈"满天星"图像,部分瘤细胞细胞核呈曲核型;免疫组化示:LCA、CD43、UCHL-1、TdT均阳性.皮肤损害示真皮浅层带状淋巴样细胞浸润,部分向表皮性,可见Pautrier微脓肿,少数淋巴样细胞细胞核呈曲核型,与淋巴结的瘤细胞相似;免疫组化示:LCA、CD43、UCHL-1均阳性,TdT阴性.原位杂交示EBER 1/2在淋巴结组织中呈阳性:皮肤组织中呈阴性.结论此例为首例报告罕见的以环形红斑为初发表现的T淋巴母细胞性淋巴瘤.
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