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Study on quality standard for Fushu granules

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Author:
No author available
Journal Title:
China Medicine
Issue:
11
DOI:
10.3760/cma.j.issn.1673-4777.2012.11.048
Key Word:
质量标准;妇舒颗粒;色谱法,薄层;色谱法,高压液相;Quality standard;Fushu granules;Chromatography,thin layer;Chromatography,high pressure liquid

Abstract: Objective To establish the quality standard for rusnu granules.Methods Flos Lonicerae Japonicae,Fructus Forsythiae,Semen Coicis,Caulis Clematidis Armandii and Pericarpium Citri Reticulatae in Fusu granules were identified by thin-layer chromatography (TLC) ; the contents of chlorogenic acid was determined by high performance liquid chromatography (HPLC).Results The spots of the five herbal drugs were well separated without interference; the linearity of chlorogenic acid was in the range of 0.16-0.80 μg,r =0.9996,and the average recovery was 97.8% ; the relative standard deviation was 2.4%.Conclusion The methods are proved to be simple with a good reproductivity and can be used to control the quality of Fushu granules.

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