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The analysis of the use of perioperative antimicrobial drug in general surgery

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Author:: CHEN Feng-en(Department of Pharmacy,First People's Hospital of Xinxiang City,Henan Province,Xinxiang 453000,China)
WANG Hua(Department of Pharmacy,First People's Hospital of Xinxiang City,Henan Province,Xinxiang 453000,China)

Journal Title:: China Medicine

Issue:: Volume 07, Issue 11, 2012

DOI:: 10.3760/cma.j.issn.1673-4777.2012.11.043

Key Word:: Perioperative period;General surgery;Anti-infective agents;Investigation and analysis;Drug monitoring

Abstract： Objective To investigate the usage of perioperative anti-infective in general surgery in our hospital and to provide references for clinical rational usage of drugs.Methods We randomly selected 259 cases in general surgery in 2010,according to the ministry of health regarding the “ clinical use of antibiotics guiding principles” in 2004,and the “the clinical use and management of antibiotics” in 2009.Results The rate of antimicrobial drug used in general surgery was 95.8％ (248/259) ; the rate in cleaning surgical was 94.1％ (176/187); the rate in clean-contaminated surgery and contaminated surgery was 100.0％ (61/61,72/72).The mean operation time was 2.1 h.94.4％ (234/248) of antimicrobial agents were used unreasonably.The top five antimicrobial drugs were cefoxitin,mezlocillin,five water cefazolin,cefotiam and levofloxacin.Conclusion There is irrational use of perioperative antimicrobial drug in general surgery.

Reference

[1]王子敏.某医院2010年门诊抗菌药物处方抽查及分析.中国基层医药,2011,18(9):1222.
[2]刁继红,廉美香.围手术期抗菌药物应用现状及管理对策.中国药业,2009,18(10):72-73.
[3]张丽辉,林俊平,张华生,等.围手术期抗菌药物应用1235例调查分析.中国全科医学,2004,7(13):981-982.
[4]褚桂芬,杨应杰,张永凤,等.循征评价妇产科围手术期预防性应用抗生素的现状.中国现代医学杂志,2006,16(22):3500-3501.
[5]贾素敏.抗菌素术前应用和术后常规应用效果比较.中国基层医药,2009,16(8):1475.
[6]许恒忠.我院外科系统预防性使用抗生素评价.中国医院用药评价与分析,2008,8(2):94-96.
[7]韩莹旻,何晶.清洁手术的药学监护.实用药物与临床,2010,13(3):215-217.
[8]裘良斌.110例普外科手术患者切口感染的因素探讨.中国医师进修杂志,2011,34(5):68-70.
[9]韩丽红,叶春林,徐丽.我院2010年某时间段医院内感染现患率调查分析.临床误诊误治,2011,24(6):88-89.
[10]May AK,Fleming SB,Carpenter RO,et al.Influence of broad-spectrum antibiotic prophylaxis on intracranial pressure monitor infections andsubsequent infectious complications in head-injured patients.Surg Infect (Larchmt),2006,7 (5):409-417.
[11]Bratzler DW,Houck PM,Surgical Infection Prevention Guidelines Writers Workgroup,et al.Antimicrobial prophylaxis for surgery:an advisory statement from the National Surgical Infection Prevention Project.Clin Infect Dis,2004,38 (12):1706-1715.
[12]李明祥.围手术期预防性使用抗菌药物250例调查.中国基层医药,2010,17(5):655.
[13]陈新谦,金有豫,汤光.新编药物学.6版.北京:人民卫生出版社,2007:56.