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Clinical effects of dezocine in preventing emergence agitation during general anesthesia

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Author:
ZHANG Yong-xiang(Department of Anesthesiology,First Affiliated Hospital,Xinxiang Medical College,Henan Province,Weihui 453100,China)
YUE Xiu-qin(Department of Anesthesiology,First Affiliated Hospital,Xinxiang Medical College,Henan Province,Weihui 453100,China)
Journal Title:
China Medicine
Issue:
Volume 07, Issue 11, 2012
DOI:
10.3760/cma.j.issn.1673-4777.2012.11.035
Key Word:
Anesthesia, general;Anesthesia recovery period;Dezocine;Postoperation

Abstract: Objective To observe the effect of dezocine preventing emergence agitation during general anesthesia.Methods Eighty patients of American Society of Anesthesiologists (ASA) Ⅰ-Ⅱ undergoing elective surgery were randomly divided into two groups:observation group and control group (40 cases in each group).The observation group was given intravenous injection of dezocine 0.1 mg/kg 30 minutes before the end of operation and patients in the control group received routine drug anesthesia.Results The incidence of Ramsay score 1 point in revive stage of general anesthesia in observation group of 5,10,20,30 min are respectively 2.5% (1/40),5.0%(2/40),5.0% (2/40),7.5 % (3/40),significandy lower than the control group,12.5 % (5/40),20.0% (8/40),30.0% (12/40),32.5% (13/40).The difference was statistically significant (all P < 0.05).Between the two groups,the breathing recovery time,eyes open time and extubation time were not statistically different (P>0.05).Conclusion Dezocine may be effective in preventing exciting and restlessness of patients recovery from general anesthesia with good consciousness and few adverse reactions.

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