Abstract： Objective To evaluate the clinical efficacy of oravive treating tooth hypersensitivity.Methods Eighty patients with teeth hypersensitivity were divided into two groups randomly. Ninety teeth were treated with oravive(test group); other 88 teeth were treated by GreenTM(control group).Clinical evaluations were repeated one and three months after product use.Results The effective teeth in test group immediately after treatment was 83,and 80 teeth were effective in control group;the effective teeth in test group one-month after treatment was 82, and 74 teeth were effective in control group,the effective cases in test group three-month after treatment was 80 teeth,and 67 teeth were effective in control group.The total effective rates of immediate treatment,one and three months after treatment in test group were 92.2％(83/90),91.1％(82/90)and 88.9％(80/90)respectively,and those of control group were 90.9％(80/88),84.1％(74/88)and 76.1％(67/88)respectively.Clinical efficacy between the two groups was significantly different at three months after treatment(P ＜ 0.05). Conclusion Oravive desensitizer can effectively relieve dentin hypersensitivity in patients with symptoms of dentine hypersensitivity,and its long-term effect is better than GreenTMOr's.