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Clinical investigation of dezocine combined with sufentanil for intravenous analgesia in cesarean section

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Author:
No author available
Journal Title:
China Medicine
Issue:
10
DOI:
10.3760/cma.j.issn.1673-4777.2012.10.045
Key Word:
地佐辛;舒芬太尼;剖宫产;静脉镇痛;Dezocine;Sufentail;Cesarean section;Intravenous analgesia

Abstract: Objective To evaluate the effects of postoperative intravenous analgesia with dezocine combined with sufentanil in cesarean section. Methods One hundred and twenty patients of society of anesthesiologists(ASA)Ⅰ-Ⅱ level were randomly divided into group DF(dozincine combined with sufentail)and group F(sufentail).Ten minutes before the surgery was finished,morphia(1-2 mg as loading dose)was injected into epidural.Patients in group DF were given docozine 10 mg + sufentanil 100 μg + tropisetron 5 mg + 0.9% NaCl;patients in group F were given sufentanil 200 μg + tropisetron 5 mg + 0.9% NaClo.Visual analogue scale(VAS),Ramsay Sedation Scale(RSS)and side effects were observed and recorded 48 hours after surgery.Results There were no significant differences in VAS between two groups(P > 0.05).The scores of RSS in group DF were higher than those in group F 1,3,6,12,24 hours after surgery.The rate of side effects was lower in group DF than that in group F[15.0%(9/60)vs 53.3%(32/60),P<0.05].Conclusion The effect of analgesia with dezocine 0.2 mg/kg combined with sufentanil 2 μg/kg is equal to that of sufentanil,and the rate of side effect is lower than that of sufentanil.

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