Correlative factors of pulmonary hypertension of hypertensive patients with isolated diastolic heart failure
- Author:
- No author available
- Journal Title:
- China Medicine
- Issue:
- 10
- DOI:
- 10.3760/cma.j.issn.1673-4777.2012.10.001
- Key Word:
- 高血压;高血压,肺性;心室功能障碍,左;Hypertension;Hypertension,pulmonary;Ventricular dysfunction,left
Abstract： Objective To explore the prevalence of pulmonary hypertension in hypertensive patients with isolated diastolic heart failure,and to analyze the related clinical features.Methods We enrolled 800 consecutive hypertensive patients with isolated diastolic heart failure.All patients underwent transthoracic doppler echocardiography to measure the pulmonary artery systolic pressure,left atrial diameter and left ventricular mass index, diastolic function indices(including transmitral and mitral annular flow,pulmonary venous flow).We divided patients into two groups:one with diastolic heart failure and concomitant pulmonary hypertension,and one with diastolic heart failure but without concomitant pulmonary hypertension.Results Compared with control group of diastolic heart failure without concomitant pulmonary hypertension,patients with pulmonary hypertension were older[(76 ±8)years old vs(63 ± 6)years old,P ＜ 0.01],more likely to have atrial fibrillation [26.7％(43/161)vs 5.8％(37/639),P ＜ 0.01],larger left atrial diameter [(49 ± 8)mm vs(38 ± 7)mm,P ＜ 0.01]and lower early mitral annular diastolic velocity [(4.9 ± 1.0)cm/s vs(6.7 ± 1.1)cm/s,P ＜0.01].Multivariate logistic regression analysis identified age,atrial fibrillation,early mitral annular diastolic velocity as the independent predictors of the presence of pulmonary hypertension.Conclusions Pulmonary hypertension is prevalent in hypertensive patients with diastolic heart failure.Age,atrial fibrillation,early mitral annular diastolic velocity are the independent predictors of the presence of pulmonary hypertension in this patient group.
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