Abstract: Objective To investigate the utilization of antibacterial drugs in the community health service center to provide clinical references for the standard management of antibacterials,and to promote rational drug use.Methods Totally 2000 case in our community health service center between January,2011 and December 2011 were randomly selected for the retrospective analysis of the use of antibacterials; 1000 patients who were discharged randomly before June 30th were chosen as control group,and those who were discharged randomly after June 30th were chosen as study group.Results Antibiotics use in the control group and study group was 46.7% and 24.4% with statistical significance(P < 0.05); irrational use of antimicrobial drugs was 58.5% and 25.0% with statistical significance (P < 0.05).Conclusions The application rate of antibacterials is high.Therefore,we should strengthen the management of antimicrobial drugs in order to promote the rational use of antimicrobial drugs.