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Clinical features of Behcet's disease complicated with pulmonary embolism and retrospective analysis

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Author:
WANG Xin-xia(Department of Respiratory Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China)
LIU Shuang(Department of Respiratory Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China)
YANG Jing-hua(Department of Respiratory Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China)
ZHU Guang-fa(Department of Respiratory Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China)
Journal Title:
China Medicine
Issue:
Volume 07, Issue 07, 2012
DOI:
10.3760/cma.j.issn.1673-4777.2012.07.018
Key Word:
Behcet's Disease;Pulmonary embolism;Thrombosis

Abstract: Objective To observe the recognition of Behcet disease(BD) complicated with pulmonary embolism(PE),and to explore the diagnosis and treatment.Methods Based on the clinical data of 3 cases of BD complicated with PE at Beijing Anzhen Hospital from 2005 to 2011,and 13 cases of BD complicated with PE reported in domestic papers from 1996 to 2011,the clinical characteristics of BD complicated with PE were analyzed and summarized retrospectively.Results BD complicated with PE were more common in young people(8/9) and in male(8/9).There were 8 cases of oral ulcers,5 cases of genital ulcers and 4 cases of skin lesions(1 case of pseudo folliculitis,3 cases of erythema nodosum).There were 1 case of positive prick test,2 cases of the eye lesions,5 cases of fever,8 cases of hemoptysis,4 cases of cough,3 cases of breathing difficulties and 5 cases of deep vein thrombosis.Erythrocyte sedimentation rate in 4 cases increased among 6 cases who had erythrocyte sedimentation rate records.The level of C-reactive protein in 7 cases increased among 8 cases who had C-reactive protein records.Pulmonary artery pressure in 2 cases increased among 4 cases who had pulmonary artery pressure records.7 cases were diagnosed of PE by CT or MRI of pulmonary angiography,2 cases were diagnosed of radionuclide lung ventilation/perfusion.Conclusion Pulmonary embolism is involved in the Behcet's disease;the treatment of the patients includes prevention of the recurrence of thrombosis.

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