Abstract： Objective To observe the clinical effect of shenqifuzheng injection on the liver function of obstructive jaundice patients after operation.Methods Forty-two patients from May 2009 to March 2011 in our hospital were randomly divided into observation group(20 cases) and control group(22 cases).The control group were treated with early enteral nutrition ( EEN ).EEN were administrated 500 ml/d at the beginning then the dose was gradually up to 1000 ml/d,while the observation group was treated with additional shenqifuzheng injection for 7 days,250 ml per day.Results The liver function indexes of alanine aminotransferase ( ALT),aspartate aminotransferase (AST) and total bilirubin (TBil) were (35 ± 19) U/L,(32 ± 16) U/L,( 27 ± 9) μmol/L in observation group 7 days after operation; they were ( 51 ± 18 ) U/L,(51 ± 1 ) U/L,(41 ± 9 ) μmol/L respectively in control group 7 days after operation; the difference between the two groups was significant (P ＜ 0.05).The nutritional status of preoperation and postoperation between the observation group and control group was not statistically significant (P ＞0.05).Conclusion Treating the liver injury after obstructive jaundice patients with shenqifuzheng injection is effective.