Abstract： Objective To compare the variation of 6-minute walk distance in patents with pulmonary hypertension combined with or without heart dysfunction,and to assess its value in identifying heart dysfunction classification.Methods Totally 164 pulmonary hypertension patients with United States New York Heart Association(NY-HA) Ⅱ-Ⅲ class who received a right heart catheter and an echocardiography exam were divided into 3 groups.Group A contained 62 patients who had post-capillary pulmonary hypertension without right heart insufficiency.Group B contained 58 patients who had pre-capillary pulmonary hypertension without right heart insufficiency.Group C contained 44 patients who had pre-capillary pulmonary hypertension companied with right heart insufficiency.6-minute walk tests were carried out in these patients and the results were analyzed.Results There were significant differences in the results of 6-minute walk distance among three groups (397 ± 112 meters in Group A,299 ±63 meters in Group B,and 294 ± 111 meter in Group C) (P ＜0.01 ).There were no differences in 6-minute walk distance between group B and group C( P ＞ 0.05 ).Conclusions 6-minute walk distance is sigrificantly reduced in pulmonary hypertension patients with heart dysfunction.However,it can not identify left heart insufficiency and right heart insufficiency.